The FDA is recommending that people decrease the amount of acetaminophen (Tylenol) they take for pain.
Acetaminophen Toxicity . My recommendation for most people is to buy the regular strength (325 mg ) pills instead of the extra strength (500 mg) acetaminophen pills. Research studies show no difference in pain relief between a couple of 325 mg pills (total of 650 mg) and a couple of 500 mg pills (total of 1000 mg) but there will be less chance of harmful liver side-effects when taking the lower dose.